A colleague of mine wants to have a small program to calculate the p-values during the course of the study for a randomized, open label study. For those who don't want to use any statistical software such as SAS, an excel spreadsheet can serve the purpose.
Calculating p-value for Fisher exact test
However, this is not a good practice and should be discouraged or prehibited. Even though this is a randomized, open label study, the study team should be restrained from continuously performing the testing based on the cumulative data.