On Biostatistics and Clinical Trials

Regulatory study data (e.g. SDTM/SEND tabulations and ADaM analysis datasets) are currently exchanged in SAS XPORT (XPT) format, the legacy ...

A box and whisker plot (Also called: box plot, box-whisker diagram) is defined as a graphical method of displaying variation in a set of da...

Randomization is the process of assigning trial subjects to treatment or control groups using an element of chance to determine the assignme...

Sometimes, it is necessary for us to calculate the p-values based on the summary (aggregate) data without the individual subject level data....

Visualizing the clinical trial data is becoming more common and various plots can be drawn to visualize the data. In previous posts, we disc...

Time to event analysis (or traditionally survival analysis) is one of the most common analyses in clinical trials. In general, the time to e...

During a clinical trial, sometimes, we are asked to select a subset of subjects from all trial participants. For example, for a clinical tri...

I am not sure how many people really know these abbreviations: DOE, IQ, OQ, PQ, PV. These are the terms used in the validation of a software...

If you work with SAS, you probably heard and used the term 'least squares means' very often. Least squares means (LS Means) are actu...