Monday, December 10, 2018

Visit Window for Longitudinal Studies

›
In the previous post, the time window was discussed. The time window is an issue in studies with relatively shorter durations (such as the ...
Monday, December 03, 2018

Time Windows for PK Blood Sampling

›
In the drug development process, especially the early non-clinical or clinical studies, it is critical to understand the DMPK. DMPK, or Dru...
5 comments:
Wednesday, November 07, 2018

FDA launches new digital tool to help capture real world data from patients to help inform regulatory decision-making

›
FDA In Brief: FDA launches new digital tool to help capture real world data from patients to help inform regulatory decision-making FDA’s My...
Thursday, November 01, 2018

Fitting Compartment Models Using PROC NLMIXED

›
There is a new article on SAS's website " Fitting Compartment Models Using PROC NLMIXED ". It is nice to know that SAS Proc NL...
Monday, October 22, 2018

Potential Unblinding due to Imbalance in Adverse Event Profiles

›
In a previous post “ Is blinded study really blinded? - assessment of blinding/unblinding in clinical trials ”, we discussed the potential...
1 comment:
Sunday, October 07, 2018

Latin Squares for Constructing "Williams Designs" - Balanced for First-order Carry-over (Residual) Effects

›
Courtesy from the website  http://statpages.info/latinsq.html , the list below contains the Williams design with 2 to 26 treatment groups. I...
3 comments:
Monday, September 10, 2018

Randomized Withdrawal Design - Examples for Defining the Criteria for Run-in and Randomized Withdrawal Periods

›
In a previous post, we discussed the " Randomized Withdrawal Design and Randomized Discontinuation Trial ". The randomized withdra...